Ishak, Siti Amirah and Djuansjah, Joy Riski Pangestu and Kadir, Mohammed Rafdiq Abdul and Sukmana, Irza (2014) Angiogenesis in tissue engineering: from concept to the vascularization of scaffold construct. IOP Conference Series: Materials Science and Engineering, 58 (1). pp. 1-6. ISSN 1757-899X

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Abstract

Angiogenesis, the formation of micro-vascular network from the preexisting vascular vessels, has been studied in the connection to the normal developmental process as well as numerous diseases. In tissue engineering research, angiogenesis is also essential to promote micro-vascular network inside engineered tissue constructs, mimicking a functional blood vessel in vivo. Micro-vascular network can be used to maintain adequate tissue oxygenation, nutrient transfer and waste removal. One of the problems faced by angiogenesis researchers is to find suitable in vitro assays and methods for assessing the effect of regulators on angiogenesis and micro-vessel formation. The assay would be reliable and repeatable with easily quantifiable with physiologically relevant. This review aims to highlights recent advanced and future challenges in developing and using an in vitro angiogenesis assay for the application on biomedical and tissue engineering research.

Item Type:	Article
Subjects:	T Technology > TJ Mechanical engineering and machinery
Divisions:	Fakultas Teknik (FT) > Prodi D3 Teknik Mesin
Depositing User:	Dr. IRZA SUKMANA
Date Deposited:	14 Aug 2017 03:04
Last Modified:	14 Aug 2017 03:04
URI:	http://repository.lppm.unila.ac.id/id/eprint/3778

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