Hadi, Sutopo (2021) The Potential Application of Diphenyltin(IV) Carboxylates as a. In: International Seminar on Traditional Herbal Medicine & Its Nanotechnology Applications, July 8-9, 2021, Bandar Lampung.
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Abstract
The organotin(IV) carboxylates and their derivatives continues to attract interest to many chemists as these compounds are very active and having strong biological activity. These compounds have previously been tested as anticancer, antimalarial, antibacterial, antifungi, and antioxidants and almost all of them have shown to be very active. Previously, some works on the synthesis and activity studies of some organotin(IV) benzoates and their derivative were reported by our group. In this work, we reported the potential applications of some diphenyltin(IV) carboxylates as disinfectant. Two bacteria, a Gram-positive Staphylococcus aereus and a Gram-negative Salmonella sp. were used in vitro in the disinfectant test with concentration variations of 5x10-3, 1x10-3 and 5x10-4 M and contact time of 5, 10 and 15 min. were performed using a control positive of a strong and common commercial disinfectant available in the market. The disinfectant activity was determined by measuring their optical density using UV-Vis spectrophotometer at max. 600 nm. The results indicated that the two diphenyltin(IV) benzoate derivatives synthesized showed much stronger disinfectant activity compared to the control positive as shown by a bigger decrease of their absorbance’s in the UV-Vis. Therefore, these two diphenyltin(IV) benzoate derivatives are potential to be used as future disinfectant
| Item Type: | Conference or Workshop Item (Speech) |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia |
| Depositing User: | Prof. Sutopo Hadi |
| Date Deposited: | 06 Nov 2021 14:01 |
| Last Modified: | 06 Nov 2021 14:01 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/35349 |
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