Hadi, Sutopo and Suhartati, Tati and Yandri, Yandri (2021) The Use of Some Organotin(IV) as Candidate for Disinfectant. In: The Virtual Conference on Chemistry and its Applications (VCCA-2021, 9-13 August 2021, Mauritius.

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Abstract

The interest in organotin(IV) carboxylates and their derivatives continues to attract many chemists as these compounds are very active and have strong biological activity [1] and they have been tested as anticancer [2,3], antimalarial [4], antibacterial [5], antifungi [6] and anti-oxidants [7]. In our previous work, the synthesis and some activity studies of organotin(IV) benzoates were reported [3-6]. In this work, we reported the potential use of some diphenyltin(IV) benzoate derivatives as disinfectant. Two bacteria, a gram-positive Staphylococcus aereus and a gram-negative Salmonella sp. were used in vitro in the disinfectant test with concentration variations of 5x10−3 , 1x10−3 and 5x10-−4 M and contact time of 5, 10 and 15 min were performed using a control positive of a strong and common commercial disinfectant available in the market. The disinfectant activity was determined by measuring their optical density using UV-Vis spectrophotometer at max 600 nm. The results indicated that the eight diphenyltin(IV) benzoate derivatives synthesized showed much stronger disinfectant activity compared to the control positive as shown by a bigger decrease of their absorbance in the UV-Vis. Therefore, these diphenyltin(IV) benzoate compounds have the potential to be used as future disinfectant

Item Type:	Conference or Workshop Item (Keynote)
Subjects:	Q Science > QD Chemistry
Divisions:	Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia
Depositing User:	Prof. Sutopo Hadi
Date Deposited:	06 Nov 2021 14:00
Last Modified:	06 Nov 2021 14:00
URI:	http://repository.lppm.unila.ac.id/id/eprint/35344

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