Hadi, Sutopo and Noviany, Noviany and Satria, Heri and Simanjuntak, Wasinton (2021) Synthesis and antimalarial activity of some triphenyltin(IV) aminobenzoate compounds against Plasmodium falciparum. Main Metal Group Chemistry, 44 (1). pp. 256-260. ISSN 2191-0219
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Abstract
This paperpresents antimalarial activity of several triphenyltin(IV) aminobenzoate compounds synthesized from the reaction of triphenyltin(IV) hydroxide with 2-, 3-, and 4-aminobenzoic acid. The activity of the compounds as anti-malaria agents was evaluated using Plasmodium falciparum, and demonstrated that the compounds have about the same IC50 with that of chloroquine (2×10-3 µg/mL) applied as the positive control. The result also showed that the Plasmodium is non-resistent to the compounds synthe�sized, which is the opposite to chloroquine
| Item Type: | Article |
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| Uncontrolled Keywords: | Antimalarial activity, IC50, triphenyltin(IV) ami�nobenzoate, P. falciparum |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia |
| Depositing User: | Prof. Sutopo Hadi |
| Date Deposited: | 04 Oct 2021 01:22 |
| Last Modified: | 04 Oct 2021 01:22 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/34246 |
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