Amrulloh, Hanif and Simanjuntak, Wasinton and Afriyani, Hapin (2021) Bioactivities of nano-scale magnesium oxide prepared using aqueous extract of Moringa Oleifera leaves as green agent. Advances in Natural Sciences: Nanoscience and Nanotechnology, 12 (015006). pp. 1-8. ISSN 2043-6262

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Abstract

In this research, nano-size MgO (NS-MgO) was prepared from MgCl solution using aqueous extract of Moringa oleifera leaves (AEMOL) as green agent. Preparation procedure involved mixing of MgCl 2 .6H 2 2 O solution and the AEMOL, followed by dropwise addition of NaOH solution. The formation of NS-MgO in this synthesis was confirmed using UV-Vis absorption. The spherical crystal structure of NS-MgO was confirmed by XRD analysis. The average particle size of the synthesised NS-MgO was found between 40–70 nm using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) images and particle size analyser (PSA) results. Based on the maximum inhibition concentration (MIC) it was found that the NS-MgO has good antibacterial activity against S. aureus, E. faecalis, E. coli, and S. dysenteriae bacteria (MIC values: 250–500 μgml−1), and much stronger antifungal activity against A. flavus, A. niger, and C. albican (MIC values: 62.5–125 μgml −1). These findings suggest prospective potential of NS-MgO synthesised as therapeutic candidate for the treatment of candidiasis.

Item Type:	Article
Subjects:	Q Science > QD Chemistry
Divisions:	Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia
Depositing User:	Prof. Wasinton Simanjuntak
Date Deposited:	03 May 2021 01:22
Last Modified:	03 May 2021 01:22
URI:	http://repository.lppm.unila.ac.id/id/eprint/29869

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