Exsa Hadibrata, exsa (2021) Tamsulosin And Sodium Diclofenac as An Effective Therapy To Reduce Pain After Ureteral Stent Removal: A Prospective, Double Blinded Randomized Placebo Controlled Trial. Urology Journal, 18 (01). pp. 111-116. ISSN 1735-1308
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Abstract
Abstract Purpose: This study was conducted to determine the effects of tamsulosin and diclofenac sodium use on patients' pain perception after ureteral stents removal. Materials and methods: This study was a randomized control trial with double-blinded design. Eighty patients who underwent ureteral stent removal surgery at Kardinah Hospital, Tegal during January to March 2017 were divided into four groups. The experimental group was administered by analgesic for two days, (A) placebo tid, or (B) diclofenac sodium 50 mg bid, or (C) tamsulosin 0.2 mg sid, or (D) combination of tamsulosin and diclofenac sodium. Analgesic effects were assessed with the Visual Analog Scale (VAS). Relationships among variables were assessed using one-way ANOVA and post hoc tests. Results: The surgical procedure for ureteral stent removal consisted of 48 (60%) male and 32 (40%) female. The average age of group A, B, C, and D were 51.0, 51.9, 47.6, and 47.3 years, and the average stent dwell times was 6.3 weeks. VAS values of the entire experimental group were lower than the control group on the first day until the second day after the stent removal procedure (p <0.05). In the experimental group, there was no difference between group B and C (p> 0.05). Group D showed better analgesic effects than group B and C (p <0.05). There were no severe side effects found in whole cases. Conclusion: The result shows that combination therapy of diclofenac sodium and tamsulosin is better in reducing the pain after ureteral stent removal compared to the admission of a single placebo, tamsulosin, and diclofenac sodium therapy.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Fakultas Kedokteran (FK) > Prodi Pendidikan Dokter |
| Depositing User: | EXSA HADIB |
| Date Deposited: | 24 Mar 2021 07:35 |
| Last Modified: | 24 Mar 2021 07:35 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/28537 |
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