Sussy, Astuti and Sutyarso, Sutyarso (2010) PENGARUH TEPUNG KEDELAI KAYA ISOFLAVON TERHADAP TESTOSTERON SERUM, JUMLAH SEL LEYDIG DAN JUMLAH SEL SPERMATOGENIC PADA TUBULI SEMINIFERI TESTIS TIKUS (Rattus norvegicus). Biota, 15 (1). pp. 31-40. ISSN 0853-8670
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Abstract
The objective of this experiment was to evaluate the effects of isoflavone-riched soybean flour with different levels of isoflavone on testosterone level, total Leydig cells, and total spermatogenic cells in the seminiferous tubules of female rats. Dies was given as isonitrogen and isocaloric with 10% of dietary protein from casein. Twenty five male of Sprague Dawley weaning rats (21 day old) were divided into five groups and treated with isoflavone-riched soybean flour by oral administration with different levels (dosages). The treatment was conducted for 2 months. The treatment of isoflavone-riched soybean floyr with higher dosage of isoflavone increased the Testosterone levels in the serum and the total Leydig cells in the seminiferous tubules of male rats. The optimum dosage of isoflavone was 1.5 mg/day resulted in the highest total spermatogenic celss of rats testes. The treatment isoflavone-riched soybean flour with 1.5 mg isoflavone/day on male rats resulted in the testosterone level of 2.6±0.45 mg/ml, total Leydig celss 70.22±9.34; while the number of spermatogonia, spermatocytes, early spermatids, late spermatids, and total spermatogenic cells were 44.44±4.82, 60.00±3.43, 221.56±16.12, 164.33±17.94, and 494.33±32.984 respectively.
| Item Type: | Article |
|---|---|
| Subjects: | R Medicine > R Medicine (General) |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi |
| Depositing User: | SUTYARSO |
| Date Deposited: | 18 Nov 2016 07:42 |
| Last Modified: | 18 Nov 2016 07:42 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/1217 |
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