Suhartati, Tati and Hernawan, Hernawan and Suwandi, Jhons Fatriyadi and Yandri, Yandri and Hadi, Sutopo (2018) SIMILARITY INDEX ISOLATION OF ARTONIN E FROM THE ROOT BARK OF ARTOCARPUS RIGIDA, SYNTHESIS OF ARTONIN E ACETATE AND EVALUATION OF ANTICANCER ACTIVITY. Institute of Chemistry, Faculty of Natural Sciences and Mathematics, Ss. Cyril & Methodius University, Skopje, Macedonia, Macedonia.
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Abstract
Artonin E was isolated from the root bark of A. rigida. The isolated compound was then esterified using a known procedure by the addition of acetic anhydride with pyridine catalyst. The structure of the synthesized compound was carefully determined by physical and spectroscopic techniques and compared to the data in the literature. The anticancer activity test against murine leukemia cancer cells P-388 showed that the ester compound has good activity with an IC50 of 2.79 μg/ml and much better stability during storage compared to artonin E itself
| Item Type: | Other |
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| Subjects: | Q Science > QD Chemistry |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia |
| Depositing User: | Prof. Tati Suhartati |
| Date Deposited: | 10 Dec 2021 01:09 |
| Last Modified: | 10 Dec 2021 01:09 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/37229 |
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