Lutfiah, Rosyidatul and Juliasih, Ni Luh Gede Ratna and Hendri, John and Setiawan, Andi Bioactivity of EtOAc Extract from Mangrove Derived Fungi as Antibacterial Agent against Staphylococcus aureus and Pseudomonas aeruginosa. The 2 nd International Conference on Chemistry, Pharmacy and Medical Sciences (ICCPM). (Unpublished)

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Abstract

The increasing cases of resistance of pathogenic bacteria to various types of antibiotics worldwide has become a serious problem for medicine and human health. Potential diversity of mangrove organisms as source for new antibacterial compounds against bacterial phatogen. In this study, fungal isolates were obtained from the mangrove ecosystem in Sriminosari area, Lampung. Fungal isolates were obtained from mud, roots, stems, and leaves of mangrove with agar diffusion technique. Fungal cultivation was carried out by the solid-state fermentation method on rice media. The cultivation and co cultivation results were extracted using ethyl acetate. The bioactivity of the extract was tested against pathogenic bacteria Pseudomonas aeruginosa and Staphylococcus aureus obtained from hospital patients. The results of the survey and isolation obtained seventeen isolate. Result of disk diffusion method showed ethyl acetat extract BA04RF1, BB04RF1, BB05RF1, CB06RF1, CB07RF1 and CD01RF1 have potential as antibacterial (100g/mL). Futhermore, fungal extract CB07RF1 showed best antibacterial activity against clinical pathogen S. aureus and P.aeruginosa with inhibition value of 14 and 12 mm respectively. This information is very important as a basis for further research on the structure and its relationship to activities.

Item Type: Article
Subjects: Q Science > Q Science (General)
Depositing User: Dr. Andi Setiawan
Date Deposited: 29 Nov 2021 01:24
Last Modified: 29 Nov 2021 01:24
URI: http://repository.lppm.unila.ac.id/id/eprint/37083

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