Andiani, Silvi and Widiastuti, E.L. and Nurcahyani, Nuning and Rosa, Emantis and Busman, Hendri (2020) CYTOTOXIC ACTIVITY OF METHANOL EXTRACTION OF AVICENNIA MARINA AND TAURIN IN THE HeLa CANCER CELLS. IOP Conf. Series: Earth and Environmental Science. ISSN 1755-1315 (In Press)

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Abstract

The aim of study was to determine any anticancer potential from Avicennia marina leaf extract compare to taurine on cytotoxic and anti-proliferation activities against HeLa cervical cancer cell line by using the MTT method (3- (4, 5-dimethylthiazol-2-yl)) - 2, 5-diphenyltetrazolium bromide). The results indicated that methanol extraction of A. marina leaf as well as taurine did have cytotoxic and anti-proliferation effects on HeLa cell line with IC50 values of 321 ppm and 603 ppm 1000 ppm. While the doubling time value for anti-proliferation of A. marina leaf methanol extraction and taurine showed higher values than the control group (72.19 hours). Keywords : Avicenia marina, taurine, cytotoxic, anti-proliferative, HeLa cells

Item Type:	Article
Subjects:	Q Science > QL Zoology
Divisions:	Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Magister Ilmu Biologi
Depositing User:	DR ENDANG LINIRIN WIDIASTUTI
Date Deposited:	19 Nov 2020 11:34
Last Modified:	19 Nov 2020 11:34
URI:	http://repository.lppm.unila.ac.id/id/eprint/26256

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