Nurcahyani, Nuning (2018) SPERMS QUALITY OF MICE DECREASED BY SEED EXTRACT OF PAPAYA (CARICA PAPAYA L.). European Journal of Biomedical and Pharmaceutical Sciences, 5 (8). pp. 95-98. ISSN 2349-8870

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ABSTRACT Objective: To enrich new evidence about the anti-fertility activity of seeds extract of papaya (Carica papaya L.) in test animals, especially mice. Methodology: Male mice (n=20) were grouped into four. The first group received only distilled water containing 1% CMC as the control. Group 2, 3 and 4 consecutively recei ved papaya seeds extract of 2, 4 and 8 mg/40 g body weight. All treatment administered orally using stomach sonde once daily for 35 days. Study parameters assessed were sperm motility, viability, and normal morphology. Results: In comparison to control group, mice injected with papaya seeds extract at the doses of 4 mg or more significantly decreased motility and normal morphology of spermatozoa. In addition, papaya seeds extract of all doses were significantly decreased percentage of sperm viability. Conclusion: Papaya seeds extract is potential to be used as male anti-fertility agent. KEYWORDS: Carica papaya, contraceptives, papaya seeds, antifertility, sperm quality.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi
Depositing User: M.Sc. Nuning Nurcahyani
Date Deposited: 08 May 2019 07:42
Last Modified: 08 May 2019 07:42

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