Busman, Hendri (2014) EFEK ANTIESTROGENIK EKSTRAK RIMPANG RUMPUT TEKI (Cyperus rotundus L.) TERHADAP KETEBALAN SEL GRANULOSA LUTEIN DAN TEKA LUTEIN KORPUS LUTEUM MENCIT (Mus musculus L.). In: Seminar Nasional dan Rapat Tahunan Bidang MIPA BKS PTN Barat, 9-11 Mei 2014, Bogor.

Prosiding Semirata 2014 IPB-HB-WAS.pdf

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One of the traditional contraceptive agents commonly used is Cyperus rotundus L which consisted of alcaloid, flavonoid glicosides and some oil. It was predicted that these substance has potential antiestrogen in which it could be used for menstruation cycle and abortion. The aims of the study was to determine the differences in the granulose lutein as well the theca lutein cells thickness of the corpus luteum of the mice ovarium. The study was conducted in zoological and chemistry laboratory of Math and Sciences Faculty, Lampung University, pathology lab of BPPV Regional III – Bandar Lampung, with 24 fertil female mice divided into 4 groups, control and treatment groups, thus each groups was replicated 6 times. The cyperus extract was orally given to the traetment groups for 14 days consecutively. The experiment applied completly randomly design with the control group (K) received 96 ml distilated water, treatment groups (Ps) received cyperus’ extract as followed: P1: 1.26 ml/40 g of bw, P2: 12.56 ml/40 g bw, P3: 37.67 ml/40 g bw. At the 15th day the mice were disected and ovaries were collected. Parameter determined was the granulose lutein as well the theca lutein cells thickness of the corpus luteum. Data was analized by using anova. The result indicated that only the treatment with 12,56 ml/40 g bw (36,306 μm) and 37,67 ml/40 g bw (32,550 μm) was able to decrease the thickness of granulosa lutein cells, while all the treatment groups decreased the thickness of theca lutein of corpus luteum in female mice. But statistically result of research not significan.

Item Type: Conference or Workshop Item (Paper)
Subjects: Q Science > QK Botany
R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi
Depositing User: M.Biomed. Hendri Busman
Date Deposited: 18 Oct 2018 03:57
Last Modified: 18 Oct 2018 03:57
URI: http://repository.lppm.unila.ac.id/id/eprint/8898

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