Kanedi, Mohammad (2018) SPERMS QUALITY OF MICE DECREASED BY SEED EXTRACT OF PAPAYA (CARICA PAPAYA L.). European Journal of Biomedical AND Pharmaceutical sciences, 5 (8). pp. 95-98. ISSN 2349-8870


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Objective: To enrich new evidence about the anti-fertility activity of seeds extract of papaya (Carica papaya L.) in test animals, especially mice. Methodology: Male mice (n=20) were grouped into four. The first group received only distilled water containing 1% CMC as the control. Group 2, 3 and 4 consecutively received papaya seeds extract of 2, 4 and 8 mg/40 g body weight. All treatment administered orally using stomach sonde once daily for 35 days. Study parameters assessed were sperm motility, viability, and normal morphology. Results: In comparison to control group, mice injected with papaya seeds extract at the doses of 4 mg or more significantly decreased motility and normal morphology of spermatozoa. In addition, papaya seeds extract of all doses were significantly decreased percentage of sperm viability. Conclusion: Papaya seeds extract is potential to be used as male anti-fertility agent.

Item Type: Article
Subjects: Q Science > Q Science (General)
R Medicine > RM Therapeutics. Pharmacology
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi
Depositing User: Drs.M.Si. Mohammad Kanedi
Date Deposited: 26 Oct 2018 10:10
Last Modified: 26 Oct 2018 10:10
URI: http://repository.lppm.unila.ac.id/id/eprint/8788

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