Pazry, Muhammad and Busman, Hendri and Nurcahyani, Nuning and SUTYARSO, SUTYARSO (2017) Potensi ekstrak Etanol Daun Pare (Momordica charantia L.) sebagai Alternativ Obat Penyembuh Luka pada Punggung Mencit Jantan ( Mus musculus). Jurnal Penelitian Pertanian Terapan, 17 (2). pp. 109-116. ISSN 1410-5020

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The leaves of bitter melon (Momordica charantia L.) Contains flavonoid, tanni and sap[onin which plays a role in wound healing. The purpose of this study was to determine the effect of bitter melon leaves (M. charantia L.) ethanolic extract on wound healing the back injury on male mice. The parametrs of this study were the lenght of wound closure and histophatological observation by looking at the level of ephiteliazation. the number of new blood vessels, and the n number of inflammatory cells. This study was conducted in a complete randomized design. yhe mice were divide into five groups : (K(+). (K(-). (P1). (P2). (p3) . each group consist four mice. all of mice was wounderd by cut on the back skin about 1,5 cm in lenght. the wound were treated every two times a day for 9 days. k(+)m is given povidone iodine as a positive control, K(-) is given 95% ethanol as a negative contol. P1 is given povidone 50% ethanolic ectract of bitter melon, P2 is given 75% athanolic extract of bitter melon and p3 is given 100% ethanolic extract of bitter melon. On the 10th day, one of the mice from all of groups was taken to observe the histopathology of their skin. the result showed that the leaf extract of bitter melon has wound healing potential by accelerate the healing process of back skin wound in mice has best histopathology picture compare to controls.

Item Type: Article
Subjects: Q Science > QL Zoology
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi
Depositing User: M.Sc. Nuning Nurcahyani
Date Deposited: 03 Aug 2018 07:28
Last Modified: 03 Aug 2018 07:28

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