Kanedi, Mohammad (2018) Potency of Leaf Extracts of Cocor Bebek (Kalanchoe pinnata) as Hair-Growth Promoting Agent. Scholars Academic Journal of Biosciences (SAJB), 6 (4). pp. 330-334. ISSN 2347-9515

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Abstract

Plant extracts of cocor bebek, Kalanchoe pinnata (Lam.) Pers., containing various types of bioactive compound expected to have cosmetic benefits, however studies on its uses in haircare is lacking. Current study is a part of our effort in extending seeks of plant species growing in Indonesia that are potent to be use as hairgrowth promoting agents. Four healthy, adult, male New Zealand rabbits, aged 4-5 months, weighing 1.5 kg – 2 kg were used as test animals. The dorsal aspect of each rabbit were shaved and divided into six areas, with a size of 2 cm x 2 cm each. Each area of shaved skin were then administered with CMC gel containing substances set for treatment namely: CMC gel without cocor bebek extract (as negative control), 2% minoxidil (as positive control), and leaf extracts of cocor bebek of four levels of concentration i.e. 25% (v/v), 50% (v/v), 75% (v/v) and 100% (v/v) respectively. Topical administration of extract was done twice a day (morning and afternoon), for 21 days. Hair length was assessed using calliper on day 7, 14 and 21 by taking randomly 10 hairs from each treatment area, while the hair mass was measured using microbalance on day 22 by harvesting all hairs on each treatment area. The result showed CMC gel containing leaf extracts of K. pinnata remarkably increased hairs length of rabbits in a concentration-related manner. At the highest concentration, the effects even surpassed minoxidil. However, no treatment found to affect hair mass of the animals. It is inferred that plant extract of cocor bebek is potential to be use as a hair growth promoting agent.

Item Type: Article
Subjects: Q Science > Q Science (General)
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi
Depositing User: Drs.M.Si. Mohammad Kanedi
Date Deposited: 21 Jun 2018 01:39
Last Modified: 21 Jun 2018 01:39
URI: http://repository.lppm.unila.ac.id/id/eprint/7383

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