Dwi Yuwono, Suripto and Mulyono, Mulyono and ., Buhani and ., Suharso and Sukmana, Irza (2017) PURIFICATION OF LACTIC ACID FROM CASSAVA BAGASSE FERMENTATION USING ION EXCHANGE. ARPN Journal of Engineering and Applied Sciences, 12 (12). pp. 3853-3857. ISSN ISSN 1819-6608

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Abstract

Polylacticacid (PLA) is used extensively for the design of drug delivery systems for peptides and vaccines, for the manufacture of medical devices and wound dressings, as well as for fabricating scaffolds in tissue engineering. Moreover, the polymer can be formulated with a variety of desirable physical properties and degradation rates, making it extremely versatile. PLA is traditionally manufactured in a three-phase process: (1) fermentation by various strains of Lactobacillus to produce lactic acid; (2) recovery of lactic acid from the fermentation broth, and (3) polymerization of the lactic acid. In this study, in order to achieve the low cost production, using the inedible waste from cassava waste as the substrate, lactic acid fermentation was conducted. Afterward, the lactic acid in the fermentation broth was separated by ion exchange resin. The model solutions were hydrolyzed to convert oligomers to monomer. The results of this research show that in batch adsorption of lactic acid (HLa) solution, the resin WA30 has the highest value of adsorbed concentration solutioncompared to the resins of Amberlite IRA A 400, SA 10A, WK 10 and PK 228. The amount of lactic acid exchanged decreases with increasing temperature. The maximum resin capability of lactic acid on WA 30 resin is much higher than the theoretical value which is separately measure with HCL method. Calculated from Langmuir equation; it was found that the adsorbed capacity for model was 128.8 mg/g-resin while for fermentation broth of 100 mg/g-resin.

Item Type: Article
Subjects: Q Science > QD Chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia
Depositing User: SUHARSO
Date Deposited: 04 Jun 2018 06:30
Last Modified: 04 Jun 2018 06:30
URI: http://repository.lppm.unila.ac.id/id/eprint/6967

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