Hendri, Busman and Winda, Trijayanthi Utama and Hanriko, Rizki and jason, Mikail Amper and Indriyni, Indriyni (2022) Effect of Ajwa Date (Phoenix dactilyfera L.) extract in aspirin induced pepticulcer model. Health Biotechnology and Biopharma, 6 (7). pp. 23-32. ISSN 2538-4414
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Abstract
Dates have been used to ameliorate various gastrointestinal diseases. This study aimed to evaluate the gastroprotective effect of ajwa dates extract on rats induced by aspirin. Rats were divided into five groups using a completely randomized design. Group 1 received only 300 mg/kg BW aspirin. Group 2 received 25.2 mg/kg BW omeprazole and aspirin 300 mg/kg BW. Groups 3, 4, and 5 received 250, 500, and 1.000 mg/kg BW ajwa dates extract and 300mg/kg BW aspirin, respectively, during 6 h. At the end of the examination, the average gaster damage score was 1.36, 0.24, 0.96, 0.68, and 0.80, in groups 1, 2, 3, 4, and 5, respectively. The 500 and 1.000 mg/kg BW doses of ajwa dates extract significantly reduced the gaster damage score. It is suggested that the extract of the ajwa date could be utilized as a gastroprotective agent. Keywords: Aspirin; Ajwa date extract; gastroprotective
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi |
| Depositing User: | M.Biomed. Hendri Busman |
| Date Deposited: | 28 Feb 2023 03:25 |
| Last Modified: | 28 Feb 2023 03:25 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/48634 |
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