Noviany, Noviany and Hadi, Sutopo (2021) Antibacterial, Anti-Oxidant and Cytotoxic Activities of the Stem Bark of Archidendron jiringa (Jack) I. C. Nielsen. In: he Virtual Conference on Chemistry and its Applications (VCCA-2021), 9-13 August 2021, Mauritius.
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Abstract
Archidendron jiringa (Jack) I. C. Nielsen is a species of the genus Archidendron, including the Fabaceae family which is known as Jengkol. Jengkol contains secondary metabolites that exhibited biological activities, such as antibacterial, antifungal, anticancer and anti-oxidant properties. This study has been carried out on extraction and fractionation of A. jiringa stem bark and tested the antibacterial, cytotoxic and anti-oxidant activity of the extract and fraction of jengkol stembark. Extraction and fractionation are conducted in several steps, including sample preparation, maceration and fractionation using vacuum liquid chromatography and column chromatography. The results of bioactivities tested performed that among three extracts obtained, ethyl acetate extract showed the most activity against B. subtilis and E. coli by using disc diffusion method. In addition, the toxicity screening displayed that all tested extracts and fractions were toxic with the LC50 values ranging of 250–750 ppm. Furthermore, all extracts and fractions showed good anti-oxidant activity with the IC50 values ranging of 0.740–7.203 ppm
| Item Type: | Conference or Workshop Item (Speech) |
|---|---|
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia |
| Depositing User: | Prof. Sutopo Hadi |
| Date Deposited: | 06 Nov 2021 14:00 |
| Last Modified: | 06 Nov 2021 14:00 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/35340 |
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