Andriani, Silvia and Widiastuti, E.L. and Nurcahyani, Nuning and Rosa, Emantis and Busman, Hendri Cytotoxic activity of methanol extraction of Avicennia marina and taurin in the HeLa cancer cells. In: ICASMI 2020 Journal of Physics: Conference Series 1751 (2021) 012045 IOP Publishing doi:10.1088/1742-6596/1751/1/012045.
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Abstract
emantisrosa@gmail.com4, hendri_busman@yahoo.com5 *Corespondi Author: Email : elwidi@yahoo.com Abstract: The aim of study was to determine any anticancer potential from Avicennia marina leaf extract compare to taurine on cytotoxic and anti-proliferation activities against HeLa cervical cancer cell line by using the MTT method (3- (4, 5-dimethylthiazol-2-yl)) - 2, 5- diphenyltetrazolium bromide). The results indicated that methanol extraction of A. marina leaf as well as taurine did have cytotoxic and anti-proliferation effects on HeLa cell line with IC50 values of 321 ppm and 603 ppm 1000 ppm. While the doubling time value for anti-proliferation of A. marina leaf methanol extraction and taurine showed higher values than the control group (72.19 hours). Keywords : Avicenia marina, taurine, cytotoxic,cytotoxic and anti-proliferative, HeLa cells
| Item Type: | Conference or Workshop Item (Paper) |
|---|---|
| Subjects: | Q Science > QL Zoology |
| Depositing User: | Dr Emantis Rosa |
| Date Deposited: | 30 May 2021 15:22 |
| Last Modified: | 30 May 2021 15:22 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/30727 |
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