Ismayati, Maya and Zulfiana, Deni and Himmi, Setiawan Khoirul and Tarmadi, Didi and Meisyara, Dita and Zulfitri, Apriwi and Kartika, Titik (2021) Antimicrobial Activity of Ten Extractives from Toba, North Sumatra and Mt. Merapi National Park Regions, Indonesia. Jurnal Sylva Lestari, 9 (1). pp. 76-85. ISSN 2549-5747

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Abstract

Investigating beneficial chemical compounds of plant extracts is one of the ways to prevent biodiversity loss. This study evaluated the antimicrobial activity of indigenous plant extracts from Toba, North Sumatra, and Mt. Merapi National Park regions against Escherichia coli, Bacillus subtilis, Salmonella typhi, Staphylococcus aureus, Candida albicans, and Candida tropicalis by calculating the zone of microbial growth inhibition. Among the plant extracts, T5 that identified asToona sinensisshowed the highestmicrobial inhibitionto the growth of C. albicans, B. subtilis, S. typhi, and E. coli with the diameter growth of approximately 2.00, 1.80, 1.33, and 1.33 cm, respectively. Based on those results, T. sinensis was thensubsequently fractionated using n-hexane, ethyl acetate, and methanol, respectively.The resulted fractions also were evaluated for antimicrobial bioassay. All fractions have shown activity in inhibiting the growth of the microbes at 1% concentration. However, each fraction showedgrowth inhibition against certain microbes. The n-hexane fraction showed the greatest inhibitory activity for E. coli and S. typhi; ethyl acetate fraction for B. subtilis and C. albicans; and methanol fraction for E. coli and S. typhi. The results revealed that T. sinensis plant extract has great potential asan antimicrobial agent. Further investigation is needed to observe the mode of antimicrobial action of fractionated crude extracts of T. Sinensis. The exploring potency of Indonesian biodiversity opened up a new way for the utilization of plants for economic development and conservation. Keywords: antimicrobial plants, indigenous knowledge, Toba-North Sumatra, Mt. Merapi

Item Type:	Article
Uncontrolled Keywords:	antimicrobial plants, indigenous knowledge, Toba-North Sumatra, Mt. Merapi
Subjects:	S Agriculture > SD Forestry
Divisions:	Fakultas Pertanian (FP) > Prodi Kehutanan
Depositing User:	Unnamed user with username syilfa lestari
Date Deposited:	25 Feb 2021 04:43
Last Modified:	25 Feb 2021 04:43
URI:	http://repository.lppm.unila.ac.id/id/eprint/28079

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