Busman, Hendri and Sutyarso, Sutyarso and Kanedi, Mohammad and Mumtazah, Dzul Fithria Sperms quality of mice effectively decreased by essential oil extracted from plant tuber of nutgrass (Cyperus rotundus). Journal of Advanced Pharmacy Education & Research. (Submitted)
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Abstract
Tuber extract of rumput teki (Cyperus rotundus), the nutgrass, has been revealed to induce apoptosis in leukemia cell lines. This effect is probably related to the essential oil content of this plant. This research aimed to determine the effect of nutgrass essential oil on the sperm quality of mice. By using a completely randomized design (CRD), test mice (n = 24) were grouped into four. Group 1 received only distilled water (control). Groups 2, 3, and 4 consecutively were treated with the essential oil at the dose of 9, 18, and 36 mg/30gBW for 35 days. By the end of treatment, the total number of sperm of mice in Groups 1 (control), 2, 3, and 4 consecuti vely were 51, 25.16, 16.66, and 11.83 million/ml. The sperm motility was 75.5%, 55.66%, 32.66%, and 23.33% respectively. The results revealed that the essential oil from nutgrass caused a decrease in the number and motility of sperm in mice in a dose-dependent manner. It is suggested that the essential oil extracted from the tuber of Cyperus rotundus is the potential to be used as antifertility. Keywords: essential oil, rumput teki, nutgrass, Cyperus rotundus, sperm quality
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > QL Zoology |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi |
| Depositing User: | M.Biomed. Hendri Busman |
| Date Deposited: | 17 Nov 2020 01:13 |
| Last Modified: | 17 Nov 2020 01:13 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/25671 |
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