Suhartati, Tati and Wulandari, Z and Wulandari, M and Yandri, Yandri and Hadi, Sutopo (2020) Identification and activity test of flavonoid compounds from wood branches of the pudau plant (Artocarpus kemando Miq.) as antibacterial. In: International Conference on Applied Sciences Mathematics and Informatics, 3-4 September 2020, Bandar Lampung.

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In this research, isolation, identification, and antibacterial bioactivity test of flavonoid compounds have been carried out. These compounds were obtained from the branches of the branches of the pudau plant originating from Karang Anyar village, Penengahan, South Lampung Regency, Lampung Province. Flavonoid compound extraction was carried out by maceration method using methanol, while fractionation and purification using chromatography. The purity of the compounds was determined by the melting point test and thin layer chromatography, the identification of compounds was carried out by UV-Vis and IR spectroscopy. The results of the isolation obtained two compounds, artocarpin (1) and cycloartocarpin (2). Compound (1), 92 mg, in the form of a yellow needle crystal with a melting point of 184.9 -187.5 °C; compound (2), 20 mg, in the form of yellowish white needle crystals with melting point 280 - 283 °C. In the antibacterial bioactivity test against Bacillus subtilis, compounds (1) had very strong antibacterial activity at a concentration of 0.4 mg/disk and against Escherichia coli in the strong category at a concentration of 0.5 mg/disk; whereas compound (2) has antibacterial activity against bacteria B. subtilis and E. coli in the strong category at a concentration of 0.5 mg/disk.

Item Type: Conference or Workshop Item (Speech)
Subjects: Q Science > QD Chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia
Depositing User: Prof. Sutopo Hadi
Date Deposited: 12 Nov 2020 08:02
Last Modified: 12 Nov 2020 08:02

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