Aisyah, Kinanti Alif Formasiyah and Setyaningrum, Endah and Pratami, Gina and Widiastuti, E.L. (2020) UJI EFEKTIVITAS SKABISIDA EKSTRAK ETANOL DAUN SIRIH (Piper betle L.) SECARA IN VIVO TERHADAP TUNGAU Sarcoptes scabiei​ PADA MARMUT (Cavia porcellus​). Jurnal Medika Malahayati, 4 (2). pp. 154-161. ISSN 2355-6757

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Abstract

Unhealthy marmot environment is one of the factors that can cause disease. One such disease is known as scabies. Scabies is caused by Sarcoptes scabiei mites that attack animals, especially on the skin. The aimof the study was to determine the effectiveness of ethanol extract of betel leaf (Piper betle L.​ ) ethanol extract in vivo against S. scabiei mites in guinea pigs (Cavia porcellus​ ). This research was conducted in October - November 2019. Sample examination, treatment and observation were carried out in the Zoology Laboratory of the Faculty of Mathematics and Natural Sciences while the making of betel leaf extract was carried out at the Botany Laboratory of the Faculty of Mathematics and Natural Sciences. The method used in this research is an experimental method with RAL (Complete Randomized Design) experiments. For scabies sample selection, microscopic examination of skin samples is carried out on guinea pigs showing clinical symptoms of scabies to confirm the presence of S. scabiei mites. The samples used were 27 marmot scabs which were relatively the same. In this study were divided into 3 treatments, namely positive control, negative control, and administration of 100% betel leaf extract. Data obtained were analyzed using One Way ANOVA and the results obtained p = 0,001 which showed a significant reduction in the wide of the scab. Then proceed with the LSD test (Least Significance Different). Based on the results and discussion, it was concluded that the administration of betel leaf ethanol extract (Piper betle L.) in vivo to Sarcoptes scabiei mites in guinea pigs (Cavia porcellus​) had the highest effectiveness as scabidae compared to 0.5% NaCMC. Keywords: Betel Leaf Extract, Guinea Pigs, Scabies

Item Type: Article
Subjects: Q Science > QL Zoology
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi
Depositing User: Dr. Endah Setyaningrum
Date Deposited: 09 Nov 2020 08:57
Last Modified: 09 Nov 2020 08:57
URI: http://repository.lppm.unila.ac.id/id/eprint/24608

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