Widiastuti, E.L. and Rima, Komang and Busman, Hendri (2020) ANTICANCER POTENCY OF HOLLY MANGROVE LEAF (Acanthus ilicifolius) METHANOL EXTRACT WITH TAURINE BY IN VITRO TEST IN CELL CULTURE OF HELA CERVICAL CANCER. IOP Conf. Series: Earth and Environmental Science. ISSN 1755-1315 (Submitted)

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Abstract

. Holly mangrove which much abundance in mangrove area, known by locals as anti-inflammatory. This study was conducted to evaluate of its action as anticancer in vitro. Holly mangrove leaf methanol extraction was proven through cytotoxic and antiproliferation tests by MTT method (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) on HeLa cervical cancer cell culture. The results indicates that the extraction had a cytotoxic activity with IC50 values are 206 ppm, while the doubling time value in the antiproliferation test indicated much higher values than the control (72.19 hours). Keywords : holly mangrove leaf, cytotoxic, antiproliferation, and HeLa cell.

Item Type: Article
Subjects: R Medicine > RS Pharmacy and materia medica
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Magister Ilmu Biologi
Depositing User: DR ENDANG LINIRIN WIDIASTUTI
Date Deposited: 01 Jun 2020 00:55
Last Modified: 01 Jun 2020 00:55
URI: http://repository.lppm.unila.ac.id/id/eprint/21313

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