Berawi, Khairun Nisa Berawi1 and Shidarti, Liana and Nurdin, Samsu Udayana (2016) COMPARISON EFFECTIVENESS OF ANTIOXIDANT ACTIVITY EXTRACT HERBAL MIXTURE OF SOURSOP LEAF (Annona muricata), BAY LEAF (Syzygium polyanthum) AND PEGAGAN LEAF (Centella asiatica). Research and Development Center of Environment Institute for Research and Community Service University of Lampung, Proceeding 3rd INTERNATIONAL WILDLIFE SYMPOSIUM. ISBN ISBN: 978-602-0860-13-8

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Abstract

Diabetes Mellitus (DM) is a degenerative disease that causes abnormal blood sugar levels are high in the body (WHO, 2010). Indonesia ranks seventh in the world as the country with the highest DM and Lampung became one of the provinces of 13 provinces with prevalence of diabetes mellitus (DM) on a national prevalence (MOH, 2013). The main problem in people with diabetes is high blood sugar levels and / or low insulin sensitivity which increase an oxidative stress levels in patient, then nutrition therapy into one of the early control of blood sugar levels. Herbs are rich in tannin and polyphenolic compounds which have effective efect as anti oxidant to improve metabolic glucose disorder and treatment for insulin sensitivity in DM. These herbs are being into alternative treatments that are often used in society. This study uses gotu kola leaf extract, soursop leaves, and the leaves to be tested effectiveness as an antioxidant that can affect blood sugar and oxidative stress conditions experienced by patients with DM.The highest yield was owned by either pegagan leaves in water and methanol extracts. The highest antioxidants activity was found in the leaves of the soursop with IC50 at the point of 0.99 mg/ml followed by a mixture of soursop bay extract 1.06 mg/ml, bay pegagan extract 1.08 mg/ml, soursop gotu kola 1.10 mg/ml, and pegagan 1.12 mg/ml. High effectiveness in inhibiting oxidative stress will improve the progression of glucose metabolic disorder due to metabolic disorders in patients with DM . Keywords: antioxidant, herbal mixture, Soursop Leaf, Bay Leaf, Pegagan Leaf

Item Type:	Book
Subjects:	Q Science > Q Science (General)
Divisions:	Fakultas Kedokteran (FK) > Prodi Pendidikan Dokter
Depositing User:	KHAIRUN NI NISA BERAWI
Date Deposited:	30 May 2017 04:52
Last Modified:	30 May 2017 04:52
URI:	http://repository.lppm.unila.ac.id/id/eprint/2000

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