Hadi, Sutopo and Noviany, Noviany (2020) Comparative Antibacterial Activity Study of Organotin(IV) 2-Nitrobenzoate. International Journal of Science and Engineering Investigations, 9 (96). pp. 48-51. ISSN 2251-8843
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Abstract
The synthesis of two organotin(IV) 2-nitrobenzoate compounds, diphenyltin(IV) di-2-nitrobenzoate (2) and triphenyltin(IV) 2-nitrobenzoate (4) have successfully been achieved by reacting the diphenyltin(IV) oxide and triphenyltin(IV) hydroxide with 2-nitrobenzoic acid. The success of synthesis was proven by spectroscopies of UV, IR and NMR, while the purity of the compounds was determined by microelemental analyzer. The antibacterial activities were carried out on positive gram bacteria S. aureus and negative gram bacteria E. coli. The result showed that compound 4 was more active than 2 giving minimum inhibition concentration of 200 ppm (3.87 x 10-4 M), while compound 2 was not active at concentration of 200 ppm. The chloramphenicol the control drug also gave inhibition at the same concentration i.e. 200 ppm, the only different is its halozone was bit bigger than the compounds tested.
| Item Type: | Article |
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| Uncontrolled Keywords: | Antibacterial, E. Coli, Organotin(IV) di-2-Nitrobenzoate, S. Aureus |
| Subjects: | Q Science > QD Chemistry |
| Divisions: | Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Magister Ilmu Kimia |
| Depositing User: | Prof. Sutopo Hadi |
| Date Deposited: | 03 Feb 2020 03:01 |
| Last Modified: | 03 Feb 2020 03:01 |
| URI: | http://repository.lppm.unila.ac.id/id/eprint/17860 |
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