Sukmana, Irza
Development of Fibrin Gel-Microgroove Model For Microvascularization by Endothelial Cells.
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Abstract
This study was performed to develop a new for study of microvascularization by endothelial cells (ECs). The effects of the width of microgrooves, initial cell seeding density and a supplementation of vascular endothe lial growth factor (VEGF) on in vitro microvasculaization formed on a polydimethylsiloxane microgroove substrate, were elongated and sprouted within the gel in all the four types of microgrooves. In addition, multicellular network serves as a geometrical constraint for ECs, with a promotional effect on angiogenic responses of ECs, and thus, it can be used as an experimental model in the study of invitro vascularization.
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Development of Fibrin Gel-Microgroove Model For Microvascularization by Endothelial Cells. (deposited 02 Jan 2020 02:13)
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