Suhartati, Tati and Yandri, AS and Suripto, Suripto and Hardoko, Insan Qudus and Sa'diah, Khalimatus (2019) ISOLATION, CHARACTERIZATION, MODIFICATION OF ARTOCARPIN COMPOUND FROM PUDAU PLANT (Artocarpus kemando Miq.) AND BIOACTIVITY ANTIBACTERIAL ASSAY OF ARTOCARPIN COMPOUND AND THEIR MODIFICATION RESULT. In: International Conference on Science, Infrastructure Technology and Regional Development, 25–26 October 2019, Institut Teknologi Sumatera campus, Lampung Selatan, Indonesia. (Submitted)

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Abstract : Artocarpus kemando Miq. is a species from Moraceae family in Indonesia know as Pudau plant. The purposes of this research are to isolate, characterize, modify and test the antibacterial activity to the artocarpin compounds isolated from pudau plants. The research stages includeed sample preparation, extraction, isolation, and purification of compounds using chromatographic techniques (TLC, VLC, and CC), characterization of compounds using spectroscopy. Isolated compound was obtained as a yellow crystal with a melting point of 185-187 oC. Based on the results of spectroscopic analysis indicated that it has been successfully isolated a prenylated flavonoid, artocarpin in the amount of 35.2 mg. The modification of artocarpin with acetic anhydride produced acetyled artocarpin as yellow crystal. Artocarpin and the modified compounds showed an antibacterial activity against Bacillus subtilis and Escherichia coli. Keywords : antibacterial, A. kemando Miq., Artocarpin, B. subtilis, E. coli

Item Type: Conference or Workshop Item (Speech)
Subjects: Q Science > QD Chemistry
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Kimia
Depositing User: Prof. Tati Suhartati
Date Deposited: 04 Nov 2019 08:28
Last Modified: 04 Nov 2019 08:28

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