Farras, Cahya Puspitha and Khairun, Nisa Berawi Free Gluten and Free Casein Diet as Therapy for Autism Spectrum Disorder. Majority, 5 (1). pp. 38-42. ISSN 2337-3776


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The increasing number of autism spectrum disorder (ASD) in Indonesia need attention. The number of ASD patient in Cipto Mangunkusumo Hospital Jakarta only found 2 patient in 1989, but in 2000 the number of ASD patient increase up to 50 times to be 103 new patient. After that, new statistic said that 0,15% child receive special education under category of autsm. ASD is a disturbance of communication, behavior, and social in children. A cause of ASD is still idiopathic, but there are multifactor such as genetic factor and environmental factor. An ASD child tends to be alone and they have their own life. Development disorder of ASD children generally appear before 3 years old, it can be difficult to have social relationship and communication to other people. ASD children known have a digestive enzyme disturbance that is sulfotrasnferase enzyme which is can cause the leak of intestinal wall so it can interference process of absorption in intestinal. The imperfect protein such as gluten dan casein normally can not be absorbed by intestinal, but because there is deficeincy of sulfotransferase enzyme it can make gluten and casein absorbed by intestine then go to blood circulation. Gluten and casein influence the behavior development of ASD children. Gluten and casein will occupy opioid receptor at central nervous system then it can trigger hyperactive behavior of ASD children. Therefore it require free gluten and free casein diet as therapy to reduce or even eliminate hyperactive behavior in ASD children. Keywords: Autism spectrum disorder, casein, gluten

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RB Pathology
Divisions: Fakultas Kedokteran (FK) > Prodi Pendidikan Dokter
Date Deposited: 16 Jan 2017 01:59
Last Modified: 16 Jan 2017 01:59
URI: http://repository.lppm.unila.ac.id/id/eprint/1396

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