Prastiwy, Ayu Ayssca Besty and Busman, Hendri and Nurcahyani, Nuning (2016) Perbandingan Obat Amaryl dengan Ekstrak Rimpang Rumput Teki(Cyperus rotundusL.)terhadap Gula Darahpada Mencit(MusmusculusL.)Jantanyang Diinduksi Aloksan. Jurnal Penelitian Pertanian Terapan, 6 (1). pp. 1-5. ISSN 1410-5020

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Abstract

ABSTRACT Nutgrass rhizome contains several chemical compounds including aetheric oil, flavonoid,saponine, and antidiabetic agents, where as amaryl is a chemical medicine used to treatdiabetes. A study about the comparison between amaryl and nut grass rhizome extract onblood sugar levels of male mice has been conducted. The study aimed to determine the effectof nut grass rhizome extract compared to amaryl in decreasing the blood sugar levels ofmale mice. The mice were divided into four groups of treatment, eachgroup consists of sixmice. The mice were intraperitoneally induced by alloxan to induce diabetes with thedosage of 0,15 mg/40 gr BB, using 0,9% of NaCl as solvent, before being given themedicine. Later, the mice were given amaryl and the nut grass rhizome extract, they weregroup 1 as control : amaryl 0,4mg/40 gr BW in 0,4 ml/100 ml of aqua bidest, group 2: nutgrass rhizome extract 4,5 mg/40 gr BB in 0,4 ml/100 ml of aqua bidest, group 3: nut grassrhizome extract 45 mg/40 gr BB in 0,4 ml/100 mlof aqua bidest, group 4: nut grass rhizomeextract 135 mg/40 gr BB in 0,4 ml/100 ml of aqua bidest. The result showed that the micegiven nut grass rhizome extract with the dosage of 135 mg/40 g BW had significantlydecreased blood sugar level compared to amaryl. This was the effect of flavoniod compoundin the nut grass rhizome extract which was rich in antioxidants so it could decrease theblood sugar levels of the diabetic mice.

Item Type: Article
Subjects: Q Science > QL Zoology
Divisions: Fakultas Matematika dan Ilmu Pengetahuan Alam (FMIPA) > Prodi Biologi
Depositing User: M.Biomed. Hendri Busman
Date Deposited: 16 Jul 2019 09:13
Last Modified: 16 Jul 2019 09:13
URI: http://repository.lppm.unila.ac.id/id/eprint/13465

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