Wardani, Dyah Wulan and Wahono, Endro Prasetyo (2019) Predominant Determinants of Delayed Tuberculosis Sputum Conversion in Indonesia. Indian Journal of Community Medicine, 44 (1). pp. 53-57. ISSN 0970-0218

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Abstract

Context: Sputum conversion in the first two months of tuberculosis (TB) treatment is closely related to successful treatment and a decrease in the likelihood of relapse. In 2015, there were 76% high TB burden countries with low rate of TB successful treatment. Aims: To evaluate the correlation between delayed sputum conversion and several determinants including: social determinants, smoking, malnutrition and type II diabetes (DM). Settings and Design: A case control approach was used to study the potential determinants. A Case sample group consisted of smear positive TB patients with delayed sputum conversion (31 patients) at community health centres in Bandar Lampung, Indonesia. Meanwhile, a control sample group consisted of smear positive TB patients with sputum conversion (62 patients). Methods and Material: Primary data consisted of social determinants and smoking, were collected through in-depth interviews. Meanwhile, secondary data, consisted of malnutrition, DM and sputum conversion were obtained from medical record. Statistical analysis used: Data was analyzed using chi square and multivariate logistic regression. Results: Low education (odds ratio/ OR: 5.313; 95% (confidence interval/ CI: 1.711–16.503), low social class (OR: 4.993; 95% CI: 1.430–17.430), smoking (OR: 7.457; 95% CI: 1.757–31.640) and DM (OR: 7.168; 95% CI: 1.746–29.431) influenced delayed sputum conversion. Conclusions: TB control programs in high TB burden countries with low rate of TB successful treatment; should be integrate TB treatment education, smoking cessation programs and follow-up treatments for TB patients with DM to improve the probability of sputum conversion and successful treatment.

Item Type:	Article
Subjects:	R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Divisions:	Fakultas Kedokteran (FK) > Prodi Pendidikan Dokter
Depositing User:	Dr. Dyah Wulan S.R. Wardani
Date Deposited:	02 May 2019 04:02
Last Modified:	02 May 2019 04:02
URI:	http://repository.lppm.unila.ac.id/id/eprint/11475

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