. The Correlation between Smoking, Alcohol and Diabetes With Degree of Histopathology of Colorectal Carcinoma in RSUD Dr. H. Abdul Moeloek Bandar Lampung In 2017-2018
Keywords:
faktor risiko, derajat histopatologi, karsinoma kolorektalAbstract
Colorectal carcinoma is a malignant neoplasm which originating or growing in the colon or rectum. Colorectal carcinoma is one of the 10 most common cancers suffered by Indonesians. Carcinomas develop much less in the duodenum, jejunum, and ileum than in the colon and rectum. The duodenum, jejunum, and ileum join the colon in the lower right abdomen. In the early stages most cancers do not show any particular clinical symptoms, however, early testing can minimize a poor prognosis. Screening or screening for colorectal carcinoma can be performed in groups of men and women over 50 years of age or patients who are at risk of developing colorectal carcinoma. Screening should also be done by people with polyps or individuals at risk of other carcinomas. The purpose of this study was to determine the frequen distribution and the relationship between smoking history, alcohol consumption history and diabetes history to the histopathological degree of colorectal carcinoma in RSUD Dr. H. Abdul Moeloek. This research was conducted in October-November 2019 at Dr. H. Abdul Moeloek Bandar Lampung using the observational method. The sample of this study consisted of 94 people with medical record data determined using total sampling techniques. Data were processed using statistical tests with a confidence level of 0.05. Chi-square test results showed that there is a correlation between smoking history (p = 0.0008), alcohol consumption (p = 0.006) and diabetes mellitus (p = 0.015) with the histopathological degree of colorectal carcinoma. So, it can be concluded there is a correlation between smoking history, alcohol consumption and diabetes.
References
Abbas AK, Aster JC, Kumar V. Buku ajar patologi ribbins. Edisi 9. Jakarta: EGC; 2015.
Aesun S. Colorectal cancer incidence in Korea is not the highest in the world. Korean Cancer Association. 2016; 48(2): 864-866
American Cancer Society. Colorectal cancer risk factor. Atlanta: American Cancer Society. 2018; [diunduh 20 September 2019]. Tersedia dari: http://www.cancer.org/cancer/ colonandrectumcancer
Brenner H, Kloor M, Pox CP. Colorectal cancer. The Lancet. 2014; 383: 1490–1502.
Deng L, Gui Z, Zhao L. Diabetes melitus and the incidence of colorectal cancer: an updated systematic review and metaanalysis. 2012; 57:1576-85.
Goel, Boland. Epigenetics of colorectal cancer. Elsevier Inc. 2012; 143(6):1442-1460
Gracia JW. Peran serat makanan dalam pencegahan kanker kolorektal. Jurnal Ukrida. 2011; 17(43): 2-7
Grady WM. Epigenetics and colorectal cancer. Nat Rev Gastroenterol Hepatol. 2011; 8(12): 686-700.
Guyton CA, Hall JE. Buku ajar fisiologi kedokteran. Edisi 11. Jakarta : Elsevier;2008.
Jensen. Adenoma detection rate and risk of colorectal cancer and death. Engl J Med. 2012; 370:1298-1306
Kemenkes RI. Pedoman nasional pelayanan kedokteran tatalaksana kanker kolorektal. Jakarta : Menteri Kesehatan RI; 2018.
Kemenkes RI. Data dan informasi kesehatan, Situasi penyakit kanker. Jakarta: Pusat Data dan Informasi Kemenkes RI; 2015.
Khosama Y. Faktor risiko kanker kolorektal. CKD-234. 2018; 42(11): 829-831
KPKN. Panduan penatalaksanaan kanker kolorektal. Jakarta : Kemenkes RI; 2017.
Kusuma HP, Adi MP. Hubungan asupan serat, lemak dan kalsium dengan kejadian karsinoma kolorektal di semarang. 2017; 5(4): 461-468
Lin. Agnostic notes on regression adjustments to experimental data: reexamining freedman’s critique. 2013; 7(1): 295-318
Moore KL, Dalley AF, Agur AM. Clinically oriented anatomy. Edisi ke-7. Philadelphia: Lippincott Williams & Wilkins; 2013.
Muflikal H, Asril Z, Aswiyanti. Profil karsinoma kolorektal di laboratorium patologi anatomi fakultas kedokteran universitas andalas priode Januari 2009 sampai Desember 2011. Jurrnal Kesehatan Andalas. 2015; 4(2): 398-400
Muhammad YL, Murdani A, Suhendro S. Probabilitas temuan kanker kolorektal pada pasien simtomatik berdasarkan unsur-unsur asia pecific colorectal screening (APCS). 2015; 2(2): 90-94
Nadia AM. Harapan terpadu kanker kolorektal. World cancer day 2018. Jakarta: Yayasan Kanker Indonesia; 2018.
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